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CD4 抗体 (mFluor™450)

This anti-CD4 antibody (ABIN6253117) is a Mouse Monoclonal antibody detecting CD4 in FACS. Suitable for Human, Rhesus Monkey, Cynomolgus.
产品编号 ABIN6253117
发货至: 中国

Quick Overview for CD4 抗体 (mFluor™450) (ABIN6253117)

抗原

See all CD4 抗体
CD4

适用

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人, 猕猴, Cynomolgus

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD4 antibody is conjugated to mFluor™450

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

OKT4
  • 原理

    CD4 mFluor™ 450 Antibody

    产品特性

    CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human peripheral blood T lymphocytes

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    CD4

    别名

    CD4

    NCBI登录号

    NM_000616

    UniProt

    P01730

    途径

    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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