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Retinoblastoma Protein (Rb) 抗体

Rb Protein 适用: 人, 小鼠 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal RB1-1754 unconjugated
产品编号 ABIN6252811
发货至: 中国
  • 抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    适用
    • 173
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    • 56
    • 8
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    • 1
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    人, 小鼠
    宿主
    • 152
    • 22
    小鼠
    克隆类型
    • 150
    • 24
    单克隆
    标记
    • 84
    • 17
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    This Retinoblastoma Protein (Rb) antibody is un-conjugated
    应用范围
    • 90
    • 89
    • 82
    • 28
    • 25
    • 15
    • 12
    • 9
    • 2
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    A human recombinant protein was used as the immunogen for this Rb antibody.
    克隆位点
    RB1-1754
    亚型
    IgG1 kappa
    Top Product
    Discover our top product Rb Protein Primary Antibody
  • 应用备注
    WB: 0.5-1 μg/mL

    IP: 1-2 μg/500 μg protein lysate

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    Titering of the Rb antibody may be required for optimal performance.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    别名
    Retinoblastoma / Rb (Rb Protein 产品)
    背景
    Recognizes a 105  kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
    基因ID
    5925
    UniProt
    P06400
    途径
    Mitotic G1-G1/S Phases
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