Retinoblastoma Protein (Rb) 抗体
-
- 抗原 See all Retinoblastoma Protein (Rb) (Rb Protein) 抗体
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Retinoblastoma Protein (Rb) antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- A human recombinant protein was used as the immunogen for this Rb antibody.
- 克隆位点
- RB1-1754
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product Rb Protein Primary Antibody
-
-
- 应用备注
-
WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg protein lysate
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Titering of the Rb antibody may be required for optimal performance. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
- 抗原
- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
- 别名
- Retinoblastoma / Rb (Rb Protein 产品)
- 背景
- Recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
- 基因ID
- 5925
- UniProt
- P06400
- 途径
- Mitotic G1-G1/S Phases
-