电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TLR4 抗体

TLR4 适用: 人, 大鼠, 犬, 猴, Pig, 豚鼠 FACS, IF, IHC (p), Func 宿主: 小鼠 Monoclonal TLR4-230 unconjugated
产品编号 ABIN6252558
发货至: 中国
  • 抗原 See all TLR4 抗体
    TLR4 (Toll-Like Receptor 4 (TLR4))
    适用
    • 177
    • 93
    • 74
    • 37
    • 22
    • 19
    • 18
    • 18
    • 5
    • 2
    • 1
    • 1
    人, 大鼠, 犬, 猴, Pig, 豚鼠
    宿主
    • 134
    • 69
    • 5
    • 4
    小鼠
    克隆类型
    • 138
    • 74
    单克隆
    标记
    • 96
    • 22
    • 20
    • 14
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLR4 antibody is un-conjugated
    应用范围
    • 155
    • 125
    • 56
    • 50
    • 34
    • 29
    • 27
    • 26
    • 26
    • 24
    • 12
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Recombinant human protein was used as the immunogen for the TLR4 antibody.
    克隆位点
    TLR4-230
    亚型
    IgG2a kappa
    Top Product
    Discover our top product TLR4 Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation)

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 1-2 μg/mL

    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    Optimal dilution of the TLR4 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    TLR4 (Toll-Like Receptor 4 (TLR4))
    别名
    TLR4 (TLR4 产品)
    别名
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    背景
    This mAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
    基因ID
    7099
    UniProt
    O00206
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
You are here:
客服