LAMP3 抗体
Quick Overview for LAMP3 抗体 (ABIN6252513)
抗原
See all LAMP3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant human protein was used as the immunogen for the LAMP3 antibody.
-
亚型
- IgG2a kappa
-
-
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 222-381) antibody
LAMP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 218-381) antibodyLAMP3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7E12C5 unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 261-310) antibodyLAMP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) antibodyLAMP3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 28-224) antibodyLAMP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (Internal Region) antibodyLAMP3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 8-38) antibodyLAMP3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) antibodyLAMP3 适用: 人 IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal LAMP3-968 unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 301-416) antibodyLAMP3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 3 (LAMP3) (AA 1-416) antibodyLAMP3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Optimal dilution of the LAMP3 antibody should be determined by the researcher. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
-
- LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))
-
别名
- LAMP3
-
背景
- This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63/LAMP3. Its epitope is different from that of mAb LAMP3/803 or LAMP3/968 or NKI/C3 or MX-49.129.5. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63/LAMP3 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. It is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63/LAMP3 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
-
基因ID
- 967
-
UniProt
- P08962
抗原
-
