LGALS1/Galectin 1 抗体 (AA 12-108)
Quick Overview for LGALS1/Galectin 1 抗体 (AA 12-108) (ABIN6252495)
抗原
See all LGALS1/Galectin 1 (LGALS1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 12-108
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纯化方法
- Protein G affinity chromatography
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免疫原
- A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.
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亚型
- IgG1 lambda
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应用备注
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ELISA: 2-4 μg/mL, order the BSA-free formulation for coating
IF: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Titering of the Galectin 1 antibody may be required for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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别名
- Galectin 1
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背景
- Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
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基因ID
- 3956
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UniProt
- P09382
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途径
- Carbohydrate Homeostasis
抗原
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