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CD1b 抗体

The 小鼠 单克隆 anti-CD1b antibody (Clone RIV12) (ABIN6252383) specifically detects CD1b in FACS, IF 和 Func. The antibody is reactive with 人 samples.
产品编号 ABIN6252383
发货至: 中国
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Quick Overview for CD1b 抗体 (ABIN6252383)

抗原

See all CD1b (CD1B) 抗体
CD1b (CD1B)

适用

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宿主

  • 32
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小鼠

克隆类型

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单克隆

标记

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This CD1b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

RIV12
  • 纯化方法

    Protein G affinity chromatography

    免疫原

    Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Functional testing: order BSA/azide free format

    IF: 0.5-1 μg/mL

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1b antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    CD1b (CD1B)

    别名

    CD1b

    背景

    This antibody recognizes CD1b, a 44  kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.

    基因ID

    910

    UniProt

    P29016
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