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CD37 抗体

TSPAN26 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal IPO-24 unconjugated
产品编号 ABIN6252308
发货至: 中国
  • 抗原 See all CD37 (TSPAN26) 抗体
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    适用
    • 66
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    宿主
    • 37
    • 30
    小鼠
    克隆类型
    • 38
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    单克隆
    标记
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    This CD37 antibody is un-conjugated
    应用范围
    • 42
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    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
    克隆位点
    IPO-24
    亚型
    IgG2b kappa
    Top Product
    Discover our top product TSPAN26 Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation)

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the CD37 antibody should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    别名
    CD37 (TSPAN26 产品)
    别名
    Tspan26 antibody, GP52-40 antibody, TSPAN26 antibody, CD37 antigen antibody, CD37 molecule antibody, Cd37 antibody, CD37 antibody
    背景
    Recognizes a protein of 33-55  kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
    基因ID
    951
    UniProt
    P11049
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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