BAFF 抗体
Our Local Distributor
北京 101111
Quick Overview for BAFF 抗体 (ABIN6251872)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
-
亚型
- IgG1
-
-
-
-
应用备注
-
Flow Cytometry: 0.5-1 μg/million cells
IF: 1-2 μg/mL
Titering of the BAFF antibody may be required for optimal performance. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
-
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
-
别名
- BAFF
-
背景
- BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
-
基因ID
- 10673
-
UniProt
- Q9Y275
-
途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
-