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ATF6 抗体 (N-Term)

Name: ATF6 抗体 (N-Term)
SKU: ABIN6251795
Availability: OutOfStock

This anti-ATF6 antibody is a 小鼠单克隆 antibody detecting ATF6 in WB 和 IHC. Suitable for 人, 小鼠和大鼠.

产品编号 ABIN6251795

发货至: 中国

Quick Overview for ATF6 抗体 (N-Term) (ABIN6251795)

抗原

See all ATF6 抗体

ATF6 (Activating Transcription Factor 6 (ATF6))

适用

人, 小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This ATF6 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

AF6229

Discover our top product ATF6 Primary Antibody

抗原表位
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1
N-Term

纯化方法

Protein G purified monoclonal antibody

免疫原

A recombinant protein fragment from the N-terminal region of human ATF6 was used as the immunogen for this antibody.

亚型

IgG1 kappa
anti-Activating Transcription Factor 6 (ATF6) (AA 1-190) antibody
ATF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibody
ATF6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibody
Verified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibody
ATF6 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibody
ATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibody
ATF6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibody
ATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated

anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibody
ATF6 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal 37-1 unconjugated

应用备注

Western blot: 2-4 μg/mL (2)

IHC (Paraffin): 5 μg/mL (1)

ATF6 is a 670 amino acid protein that migrates in western blot between 70~90 kD due to glycosylation.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. ATF6 is seen in western blotting between 75~90KD.

限制

仅限研究用
状态

Liquid

浓度

0.5 mg/mL

缓冲液

PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Aliquot and Store at -20C. Avoid freez-thaw cycles.
抗原

ATF6 (Activating Transcription Factor 6 (ATF6))

别名

ATF6

背景

ER stress can cause the accumulation of unfolded proteins and lead to the activation of the UPR (unfolded proetin response). Cells have developed an intracellular signaling pathway to deal with this stress, and Activating Transcription Factor 6 (ATF6) is a major transducer of the UPR. Upon activation, ATF6 seperates from GPR78 and is cleaved. The ~50 kD cytosolic portion of ATF6 translocates to the nucleus, transmitting the ER stress signal. In the nucleus, ATF6 activates the transcription of UPR-responsive genes by biniding to their ERSE (ER stress response element) region.

基因ID

22926

UniProt

P18850

途径

ER-Nucleus Signaling, Unfolded Protein Response