ATF6 抗体 (N-Term)
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北京 101111
Quick Overview for ATF6 抗体 (N-Term) (ABIN6251795)
抗原
See all ATF6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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纯化方法
- Protein G purified monoclonal antibody
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免疫原
- A recombinant protein fragment from the N-terminal region of human ATF6 was used as the immunogen for this antibody.
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亚型
- IgG1 kappa
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anti-Activating Transcription Factor 6 (ATF6) (AA 1-190) antibody
ATF6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 1-377) antibodyATF6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 437-449) antibodyVerified ATF6 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 301-400) antibodyATF6 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22035 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 350-377) antibodyATF6 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 423-646) antibodyATF6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activating Transcription Factor 6 (ATF6) (AA 91-193) antibodyATF6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 1-7 unconjugated
anti-Activating Transcription Factor 6 (ATF6) (N-Term) antibodyATF6 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal 37-1 unconjugated
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应用备注
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Western blot: 2-4 μg/mL (2)
IHC (Paraffin): 5 μg/mL (1)
ATF6 is a 670 amino acid protein that migrates in western blot between 70~90 kD due to glycosylation.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. ATF6 is seen in western blotting between 75~90KD. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- ATF6 (Activating Transcription Factor 6 (ATF6))
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别名
- ATF6
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背景
- ER stress can cause the accumulation of unfolded proteins and lead to the activation of the UPR (unfolded proetin response). Cells have developed an intracellular signaling pathway to deal with this stress, and Activating Transcription Factor 6 (ATF6) is a major transducer of the UPR. Upon activation, ATF6 seperates from GPR78 and is cleaved. The ~50 kD cytosolic portion of ATF6 translocates to the nucleus, transmitting the ER stress signal. In the nucleus, ATF6 activates the transcription of UPR-responsive genes by biniding to their ERSE (ER stress response element) region.
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基因ID
- 22926
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UniProt
- P18850
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途径
- ER-Nucleus Signaling, Unfolded Protein Response
抗原
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