FAT Atypical Cadherin 2 (FAT2) 抗体
The 小鼠 单克隆 anti-FAT Atypical Cadherin 2 antibody (Clone 8C5) (ABIN6251792) specifically detects FAT Atypical Cadherin 2 in FACS, IF, IHC 和 WB.
The antibody is reactive with 人 samples.
产品编号 ABIN6251792
发货至:
中国
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中国
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Quick Overview for FAT Atypical Cadherin 2 (FAT2) 抗体 (ABIN6251792)
抗原
See all FAT Atypical Cadherin 2 (FAT2) 抗体
FAT Atypical Cadherin 2 (FAT2)
适用
人
宿主
小鼠
克隆类型
单克隆
标记
非结合性
应用范围
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
克隆位点
8C5
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human Protocadherin Fat 2 fusion protein was used as the immunogen for this FAT2 antibody.
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亚型
- IgG1 kappa
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anti-FAT Atypical Cadherin 2 (FAT2) antibody
FAT2 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal 8C5 unconjugated
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT
Titering of the FAT2 antibody may be required for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- FAT Atypical Cadherin 2 (FAT2)
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别名
- FAT2
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背景
- Recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
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基因ID
- 2196
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UniProt
- Q9NYQ8
抗原
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