SIX Homeobox 1 抗体 (AA 69-102)
Quick Overview for SIX Homeobox 1 抗体 (AA 69-102) (ABIN6244222)
抗原
See all SIX Homeobox 1 (SIX1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 69-102
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SIX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 69-102 amino acids from the Central region of human SIX1.
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亚型
- Ig Fraction
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anti-SIX Homeobox 1 (SIX1) antibody
SIX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (Middle Region) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 144-262) antibodySIX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (C-Term) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 绵羊, Pig, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 1-284) antibodySIX1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-SIX Homeobox 1 (SIX1) (Internal Region) antibodySIX1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (AA 60-270) antibodySIX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SIX Homeobox 1 (SIX1) (N-Term) antibodySIX1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, 绵羊, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- SIX Homeobox 1 (SIX1)
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别名
- SIX1
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背景
- Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.
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分子量
- 32210
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UniProt
- Q15475
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途径
- Sensory Perception of Sound, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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