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DKK2 抗体

The 小鼠 单克隆 anti-DKK2 antibody (Clone 1833CT856-7-20) (ABIN6244156) specifically detects DKK2 in WB. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6244156
发货至: 中国
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Quick Overview for DKK2 抗体 (ABIN6244156)

抗原

See all DKK2 抗体
DKK2 (Dickkopf 2 Homolog (DKK2))

适用

  • 52
  • 16
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 47
  • 4
  • 1
小鼠

克隆类型

  • 48
  • 4
单克隆

标记

  • 28
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DKK2 antibody is un-conjugated

应用范围

  • 38
  • 24
  • 23
  • 7
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB)

克隆位点

1833CT856-7-20
  • 纯化方法

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    免疫原

    This DKK2 antibody is generated from a mouse immunized with a recombinant protein of human DKK2.

    亚型

    IgG1 kappa
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    DKK2 (Dickkopf 2 Homolog (DKK2))

    别名

    DKK2

    背景

    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

    分子量

    28447

    UniProt

    Q9UBU2

    途径

    WNT signaling
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