ATG10 抗体 (N-Term)
(1 reference)Quick Overview for ATG10 抗体 (N-Term) (ABIN6244154)
抗原
See all ATG10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 15-45, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ATG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15~45 amino acids from the N-term of human APG10L.
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亚型
- Ig Fraction
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anti-Autophagy Related 10 (ATG10) (AA 1-125) antibody
ATG10 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 8A9B3 unconjugated
anti-Autophagy Related 10 (ATG10) (AA 1-220) antibodyATG10 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 10 (ATG10) antibodyATG10 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 10 (ATG10) (AA 1-50) antibodyATG10 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 10 (ATG10) antibodyATG10 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Autophagy Related 10 (ATG10) (C-Term) antibodyATG10 适用: 人, 犬, 兔, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 10 (ATG10) (C-Term) antibodyATG10 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 10 (ATG10) antibodyATG10 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).
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: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).
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- ATG10 (Autophagy Related 10 (ATG10))
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别名
- ATG10
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG10 is an ATG12-conjugating enzyme (E2-like enzyme) that likely serves as an ATG5-recognition molecule. This protein interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. APG10 also is able to directly interact either with ATG5 or ATG7.
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分子量
- 25279
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NCBI登录号
- NP_001124500, NP_113670
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UniProt
- Q9H0Y0
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途径
- ER-Nucleus Signaling, Autophagy
抗原
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