RSPO1 抗体 (AA 206-240)
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北京 101111
Quick Overview for RSPO1 抗体 (AA 206-240) (ABIN6244080)
抗原
See all RSPO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 206-240
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RSPO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from human RSPO1.
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亚型
- Ig Fraction
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anti-R-Spondin 1 (RSPO1) (AA 21-135) antibody
RSPO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 136-262) antibodyRSPO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-263) antibodyRSPO1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7A6 unconjugated
anti-R-Spondin 1 (RSPO1) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (AA 21-135) antibodyRSPO1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-R-Spondin 1 (RSPO1) (N-Term) antibodyRSPO1 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RSPO1 (R-Spondin 1 (RSPO1))
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别名
- RSPO1
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背景
- Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.
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分子量
- 28959
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UniProt
- Q2MKA7
抗原
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