RICTOR 抗体 (AA 1068-1102)
Quick Overview for RICTOR 抗体 (AA 1068-1102) (ABIN6243989)
抗原
See all RICTOR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1068-1102
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RICTOR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1068-1102 amino acids from the Central region of human RICTOR.
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亚型
- Ig Fraction
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anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-98) antibody
RICTOR 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7B3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (C-Term) antibodyRICTOR 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-245) antibodyRICTOR 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) antibodyRICTOR 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-99) antibodyRICTOR 适用: 人 WB, ELISA, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1-265) antibodyRICTOR 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 252-281), (N-Term) antibodyRICTOR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11675 unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 236-267) antibodyRICTOR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RPTOR Independent Companion of mTOR, Complex 2 (RICTOR) (AA 1617-1650) antibodyRICTOR 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))
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别名
- RICTOR
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背景
- Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient- insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development.
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分子量
- 192218
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UniProt
- Q6R327
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events
抗原
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