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RENT1/UPF1 抗体 (AA 583-612)

Cited in 1 publication. This anti-RENT1/UPF1 antibody is a 兔 多克隆 antibody detecting RENT1/UPF1 in WB. Suitable for 人.
产品编号 ABIN6243988
发货至: 中国
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Quick Overview for RENT1/UPF1 抗体 (AA 583-612) (ABIN6243988)

抗原

See all RENT1/UPF1 (UPF1) 抗体
RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This RENT1/UPF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB8354
  • 抗原表位

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    AA 583-612

    预测反应

    M

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 583-612 amino acids from the Central region of human RENT1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Tian, Macdonald et al.: "The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 ..." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 17, pp. 5937-52, (2012) (PubMed).

  • 抗原

    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

    别名

    RENT1

    背景

    RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.

    分子量

    124345

    NCBI登录号

    NP_002902

    UniProt

    Q92900

    途径

    SARS-CoV-2 Protein Interactome
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