SPPL2B 抗体 (AA 196-229)
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北京 101111
Quick Overview for SPPL2B 抗体 (AA 196-229) (ABIN6243975)
抗原
See all SPPL2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 196-229
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the Central region of human SPPL2B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))
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别名
- SPPL2B
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背景
- Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.
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分子量
- 64644
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UniProt
- Q8TCT7
抗原
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