PROX1 抗体 (AA 444-478)
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北京 101111
Quick Overview for PROX1 抗体 (AA 444-478) (ABIN6243958)
抗原
See all PROX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 444-478
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PROX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 444-478 amino acids from the Central region of human PROX1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PROX1 (Prospero Homeobox 1 (PROX1))
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别名
- PROX1
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背景
- Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
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分子量
- 83203
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UniProt
- Q92786
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
抗原
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