EPH Receptor B3 抗体 (AA 350-382)
Quick Overview for EPH Receptor B3 抗体 (AA 350-382) (ABIN6243857)
抗原
See all EPH Receptor B3 (EPHB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 350-382
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Ephb3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 350-382 amino acids from the Central region of Mouse Ephb3.
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亚型
- Ig Fraction
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anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibody
EPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F12 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibodyEPHB3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4A122D1 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 650-700) antibodyEPHB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 261-390) antibodyEPHB3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) antibodyEPHB3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 552-601) antibodyEPHB3 适用: 人, 犬, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-998) antibodyEPHB3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-EPH Receptor B3 (EPHB3) antibodyEPHB3 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB16728 unconjugated
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应用备注
- WB: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- EPH Receptor B3 (EPHB3)
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别名
- Ephb3
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背景
- Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. Beside its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.
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分子量
- 109662
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UniProt
- P54754
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途径
- RTK signaling
抗原
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