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RAD21 抗体 (AA 501-535)

This anti-RAD21 antibody is a 兔 多克隆 antibody detecting RAD21 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6243856
发货至: 中国

Quick Overview for RAD21 抗体 (AA 501-535) (ABIN6243856)

抗原

See all RAD21 抗体
RAD21 (RAD21 Homolog (RAD21))

适用

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人, 小鼠, 大鼠

宿主

  • 52
  • 4
  • 1

克隆类型

  • 46
  • 12
多克隆

标记

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This RAD21 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB56184
  • 抗原表位

    • 16
    • 12
    • 5
    • 2
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    • 1
    • 1
    • 1
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    • 1
    AA 501-535

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RAD21 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 501-535 amino acids from human RAD21.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    RAD21 (RAD21 Homolog (RAD21))

    别名

    RAD21

    背景

    Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

    分子量

    71690

    UniProt

    O60216

    途径

    Positive Regulation of Endopeptidase Activity
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