PARK7/DJ1 抗体 (C-Term)
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北京 101111
Quick Overview for PARK7/DJ1 抗体 (C-Term) (ABIN6243855)
抗原
See all PARK7/DJ1 (PARK7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 130-164, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PARK7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 130-164 amino acids from the C-terminal region of human PARK7.
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亚型
- Ig Fraction
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anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibody
PARK7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (C-Term) antibodyVerified PARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 101-189) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (C-Term) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibodyPARK7 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-188) antibodyPARK7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibodyPARK7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibodyPARK7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibodyPARK7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 7 (PARK7) (AA 1-100) antibodyPARK7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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别名
- PARK7
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背景
- Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Stabilizes NFE2L2 by preventing its association with KEAP1 and its subsequent ubiquitination. Binds to OTUD7B and inhibits its deubiquitinating activity. Enhances RELA nuclear translocation. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone. May regulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells.
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分子量
- 19891
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UniProt
- Q99497
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
抗原
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