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KANK2 抗体 (AA 343-376)

KANK2 适用: 人 WB 宿主: 兔 Polyclonal RB48827 unconjugated
产品编号 ABIN6243798
发货至: 中国
  • 抗原 See all KANK2 products
    KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))
    抗原表位
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 343-376
    适用
    • 36
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KANK2 antibody is un-conjugated
    应用范围
    • 21
    • 18
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This KANK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-376 amino acids from the Central region of human KANK2.
    克隆位点
    RB48827
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))
    别名
    KANK2 (KANK2 产品)
    别名
    ANKRD25 antibody, MXRA3 antibody, SIP antibody, AI504612 antibody, Ankrd25 antibody, BC010245 antibody, KN motif and ankyrin repeat domains 2 antibody, KANK2 antibody, Kank2 antibody
    背景
    Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:< a href="http://www.uniprot.org/citations/24671081" target="_blank">24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:< a href="http://www.uniprot.org/citations/22371500" target="_blank">22371500). May be involved in promotion of cell proliferation (By similarity).
    分子量
    91174
    UniProt
    Q63ZY3
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