KANK2 抗体 (AA 343-376)
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北京 101111
Quick Overview for KANK2 抗体 (AA 343-376) (ABIN6243798)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 343-376
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KANK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-376 amino acids from the Central region of human KANK2.
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亚型
- Ig Fraction
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anti-KN Motif and Ankyrin Repeat Domains 2 (KANK2) (AA 1-300) antibody
KANK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-KN Motif and Ankyrin Repeat Domains 2 (KANK2) (AA 410-585) antibodyKANK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-KN Motif and Ankyrin Repeat Domains 2 (KANK2) (AA 696-745) antibodyKANK2 适用: 人, 小鼠, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-KN Motif and Ankyrin Repeat Domains 2 (KANK2) (AA 351-400) antibodyKANK2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- KANK2 (KN Motif and Ankyrin Repeat Domains 2 (KANK2))
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别名
- KANK2
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背景
- Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm, the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:< a href="http://www.uniprot.org/citations/24671081" target="_blank">24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis, proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:< a href="http://www.uniprot.org/citations/22371500" target="_blank">22371500). May be involved in promotion of cell proliferation (By similarity).
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分子量
- 91174
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UniProt
- Q63ZY3
抗原
-
