LIN28A 抗体 (AA 85-119)
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北京 101111
Quick Overview for LIN28A 抗体 (AA 85-119) (ABIN6243716)
抗原
See all LIN28A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 85-119
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DANRE lin28a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 85-119 amino acids from the Central region of DANRE lin28a.
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亚型
- Ig Fraction
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anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 108-138) antibody
LIN28A 适用: 人, 小鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14827 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (N-Term) antibodyLIN28A 适用: 人, Cow, 犬, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 93-209) antibodyLIN28A 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D1F9 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 108-138) antibodyLIN28A 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 142-209) antibodyLIN28A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) antibodyLIN28A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 168-198), (C-Term) antibodyLIN28A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14266 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 177-210), (C-Term) antibodyLIN28A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51168 unconjugated
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) antibodyKD Validated LIN28A 适用: 人 WB 宿主: 兔 Monoclonal 25GB2520 unconjugated Recombinant Antibody
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (AA 1-209) antibodyLIN28A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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别名
- lin28a
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背景
- Acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting an uridylyltransferase, leading to the terminal uridylation of pre- let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation (By similarity).
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分子量
- 21886
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UniProt
- Q803L0
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途径
- Stem Cell Maintenance
抗原
-
