GRF2 抗体 (AA 536-569)
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北京 101111
Quick Overview for GRF2 抗体 (AA 536-569) (ABIN6243613)
抗原
See all GRF2 (RAPGEF1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 536-569
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RAPGEF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 536-569 amino acids from the Central region of human RAPGEF1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000-1:2000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
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别名
- RAPGEF1
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背景
- Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
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分子量
- 120548
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UniProt
- Q13905
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途径
- Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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