电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CSK 抗体 (N-Term)

This anti-CSK antibody is a 兔 多克隆 antibody detecting CSK in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6243610
发货至: 中国

Quick Overview for CSK 抗体 (N-Term) (ABIN6243610)

抗原

See all CSK 抗体
CSK (C-Src tyrosine Kinase (CSK))

适用

  • 105
  • 57
  • 46
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 94
  • 10
  • 3

克隆类型

  • 92
  • 14
多克隆

标记

  • 56
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CSK antibody is un-conjugated

应用范围

  • 96
  • 41
  • 26
  • 26
  • 18
  • 16
  • 13
  • 9
  • 9
  • 7
  • 6
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB50498
  • 抗原表位

    • 18
    • 16
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-51, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CSK antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 17-51 amino acids from the N-terminal region of human CSK.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    CSK (C-Src tyrosine Kinase (CSK))

    别名

    CSK

    背景

    Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK.

    分子量

    50704

    UniProt

    P41240

    途径

    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
You are here:
Chat with us!