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FLT3 抗体 (AA 474-510)

This anti-FLT3 antibody is a 兔多克隆 antibody detecting FLT3 in WB. Suitable for 人和小鼠.

Western blot analysis of lysates from Daudi cell line and mouse testis tissue (from left to right), using FLT3 Antibody (Center) (ABIN6243524 and ABIN6577687). (FLT3 抗体 (AA 474-510))

1 image

产品编号 ABIN6243524

发货至: 中国

Quick Overview for FLT3 抗体 (AA 474-510) (ABIN6243524)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

144
43
6
5
1
1
1
1
1
1

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

77
12
9
7
6
4
3
3
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1

This FLT3 antibody is un-conjugated

应用范围

114
69
42
42
38
34
19
12
11
10
8
8
3
2
1
1
1
1
1

Western Blotting (WB)

克隆位点

RB50841

Discover our top product FLT3 Primary Antibody

抗原表位
19

18

17

12

9

8

7

6

5

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 474-510

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This FLT3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 474-510 amino acids from the Central region of human FLT3.

亚型

Ig Fraction
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

FLT3

背景

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

分子量

112903

UniProt

P36888

途径

RTK signaling

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