ALK 抗体 (C-Term)
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北京 101111
Quick Overview for ALK 抗体 (C-Term) (ABIN6243476)
抗原
See all ALK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1591-1620, C-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK.
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亚型
- Ig Fraction
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anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 636-666) antibody
ALK 适用: 人 IHC (p), WB 宿主: 兔 Polyclonal RB15425 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 14-43), (N-Term) antibodyALK 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB1511-1512 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 636-666) antibodyALK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1466-1500), (C-Term) antibodyALK 适用: 人 WB 宿主: 兔 Polyclonal RB50500 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1517-1550) antibodyALK 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50288 unconjugated
anti-Anaplastic Lymphoma Receptor tyrosine Kinase (ALK) (AA 1517-1550) antibodyALK 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 116-25, (2016) (PubMed).
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: "Crizotinib reduces the rate of dark adaptation in the rat retina independent of ALK inhibition." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 143, Issue 1, pp. 116-25, (2016) (PubMed).
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- ALK (Anaplastic Lymphoma Receptor tyrosine Kinase (ALK))
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别名
- ALK
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背景
- ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2,5)(p23,q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
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分子量
- 176442
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NCBI登录号
- NP_004295
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UniProt
- Q9UM73
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途径
- RTK signaling
抗原
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