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HTR2A 抗体 (N-Term)

This 兔 多克隆 anti-HTR2A antibody (Clone RB52772) specifically detects HTR2A in WB 和 IHC (p). The antibody is reactive with 小鼠 samples.
产品编号 ABIN6243464
发货至: 中国
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Quick Overview for HTR2A 抗体 (N-Term) (ABIN6243464)

抗原

See all HTR2A 抗体
HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

适用

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  • 1
小鼠

宿主

  • 74
  • 1
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克隆类型

  • 76
  • 1
多克隆

标记

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This HTR2A antibody is un-conjugated

应用范围

  • 55
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB52772
  • 抗原表位

    • 16
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    AA 16-30, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Htr2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human Htr2a.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

    别名

    Htr2a

    背景

    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca(2+) ions from intracellular stores. Affects neural activity, perception, cognition and mood. Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

    分子量

    52842

    UniProt

    P35363

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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