电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

KAT5 抗体 (AA 367-398)

This anti-KAT5 antibody is a 兔 多克隆 antibody detecting KAT5 in WB. Suitable for 人.
产品编号 ABIN6243420
发货至: 中国

Quick Overview for KAT5 抗体 (AA 367-398) (ABIN6243420)

抗原

See all KAT5 抗体
KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

适用

  • 88
  • 64
  • 55
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 103
  • 15

克隆类型

  • 104
  • 15
多克隆

标记

  • 60
  • 8
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This KAT5 antibody is un-conjugated

应用范围

  • 88
  • 57
  • 27
  • 27
  • 25
  • 18
  • 10
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB53893
  • 抗原表位

    • 17
    • 15
    • 13
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 367-398

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This KAT5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-398 amino acids from human KAT5.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

    别名

    KAT5

    背景

    Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Directly acetylates and activates ATM. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation. Relieves NR1D2-mediated inhibition of APOC3 expression by acetylating NR1D2.

    分子量

    58582

    UniProt

    Q92993

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
You are here:
Chat with us!