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KAT5 抗体

KAT5 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3F9 unconjugated
产品编号 ABIN1724672
发货至: 中国
  • 抗原 See all KAT5 抗体
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    适用
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    宿主
    • 101
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    小鼠
    克隆类型
    • 102
    • 11
    单克隆
    标记
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    This KAT5 antibody is un-conjugated
    应用范围
    • 84
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human TIP60 expressed in E. coli.
    克隆位点
    3F9
    亚型
    IgG2b
    Top Product
    Discover our top product KAT5 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Raisner, Madhani: "Patterning chromatin: form and function for H2A.Z variant nucleosomes." in: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).

    Jin, Cai, Li, Conaway, Workman, Conaway, Kusch: "In and out: histone variant exchange in chromatin." in: Trends in biochemical sciences, Vol. 30, Issue 12, pp. 680-7, (2005) (PubMed).

  • 抗原
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    别名
    TIP60 (KAT5 产品)
    别名
    6121 antibody, CG6121 antibody, DmEG0007.7 antibody, Dmel/TIP60 antibody, Dmel\\CG6121 antibody, Dmel\\TIP60 antibody, EG0007.7 antibody, EG:EG0007.7 antibody, TIP60 antibody, dTIP60 antibody, dTip60 antibody, dmHAG405 antibody, im:6908768 antibody, wu:fb55b08 antibody, zgc:110752 antibody, ESA1 antibody, HTATIP antibody, HTATIP1 antibody, PLIP antibody, TIP antibody, ZC2HC5 antibody, cPLA2 antibody, AI839539 antibody, CPLA2 antibody, Htatip antibody, Htatip1 antibody, Tip55 antibody, Tip60 antibody, K(lysine) acetyltransferase 5a antibody, lysine acetyltransferase 5 antibody, Tat interactive protein 60kDa antibody, histone acetyltransferase Tip60 antibody, tip60, putative antibody, K(lysine) acetyltransferase 5b antibody, K(lysine) acetyltransferase 5 antibody, kat5a antibody, KAT5 antibody, Tip60 antibody, LOC413101 antibody, LOC5579231 antibody, Smp_053140 antibody, kat5b antibody, Kat5 antibody
    背景

    Description: HTATIP (HIV-1 Tat interacting protein TIP60, about 60 kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

    Aliases: TIP60 (HTATIP)

    分子量
    60 kDa
    基因ID
    10524
    HGNC
    10524
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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