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UBE2D2 抗体 (N-Term)

This 兔 多克隆 anti-UBE2D2 antibody (Clone RB49628) specifically detects UBE2D2 in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6243331
发货至: 中国
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Quick Overview for UBE2D2 抗体 (N-Term) (ABIN6243331)

抗原

See all UBE2D2 抗体
UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

适用

  • 62
  • 33
  • 17
  • 8
  • 7
  • 6
  • 6
  • 6
  • 6
  • 4
  • 3
  • 3
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  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 7

克隆类型

  • 56
  • 6
多克隆

标记

  • 33
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
  • 1
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This UBE2D2 antibody is un-conjugated

应用范围

  • 50
  • 23
  • 13
  • 13
  • 9
  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB49628
  • 抗原表位

    • 15
    • 9
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-76, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This UBE2D2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-76 amino acids from the N-terminal region of human UBE2D2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

    别名

    UBE2D2

    背景

    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

    分子量

    16735

    UniProt

    P62837

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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