ULK3 抗体 (C-Term)
Quick Overview for ULK3 抗体 (C-Term) (ABIN6243328)
抗原
See all ULK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 435-468, C-Term
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This ULK3 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 435-468 amino acids from the C-terminal region of human ULK3.
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亚型
- IgG1 kappa
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anti-Unc-51-Like Kinase 3 (ULK3) (Internal Region) antibody
ULK3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 427-454), (C-Term) antibodyULK3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibodyULK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 44-240) antibodyULK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 1-214) antibodyULK3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 445-458) antibodyVerified ULK3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (C-Term) antibodyVerified ULK3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 324-373) antibodyULK3 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC: 1:50. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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别名
- ULK3
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背景
- Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
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分子量
- 53444
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UniProt
- Q6PHR2
抗原
-
