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IFITM3 抗体 (N-Term)

IFITM3 适用: 人 WB 宿主: 小鼠 Monoclonal 1082CT14-1-3-1 unconjugated
产品编号 ABIN6243232
发货至: 中国
  • 抗原 See all IFITM3 抗体
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    抗原表位
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-133, N-Term
    适用
    • 38
    • 6
    • 5
    • 1
    • 1
    • 1
    宿主
    • 30
    • 5
    • 3
    小鼠
    克隆类型
    • 33
    • 5
    单克隆
    标记
    • 26
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFITM3 antibody is un-conjugated
    应用范围
    • 28
    • 19
    • 11
    • 11
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This IFITM3 antibody is generated from a mouse immunized with a recombinant protein KLH conjugated synthetic peptide between 1-133 amino acids from the N-terminal region of human IFITM3.
    克隆位点
    1082CT14-1-3-1
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IFITM3 Primary Antibody
  • 应用备注
    WB: 1:4000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
    别名
    IFITM3 (IFITM3 产品)
    别名
    1110004C05Rik antibody, Cd225 antibody, Cdw217 antibody, DSPA2b antibody, Fgls antibody, IP15 antibody, mil-1 antibody, 1-8U antibody, rat8 antibody, Interferon-induced transmembrane protein 3 antibody, interferon induced transmembrane protein 3 antibody, ifm3 antibody, Ifitm3 antibody, IFITM3 antibody
    背景
    IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
    分子量
    14632
    UniProt
    Q01628
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