IFITM3 抗体 (N-Term)
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Quick Overview for IFITM3 抗体 (N-Term) (ABIN6243232)
抗原
See all IFITM3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-133, N-Term
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This IFITM3 antibody is generated from a mouse immunized with a recombinant protein KLH conjugated synthetic peptide between 1-133 amino acids from the N-terminal region of human IFITM3.
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亚型
- IgG1 kappa
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anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibody
IFITM3 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-30), (N-Term) antibodyIFITM3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13975 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H4-1D5 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8-1B10 unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-57) antibodyIFITM3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (Internal Region) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (AA 1-133) antibodyIFITM3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyIFITM3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon-Induced Transmembrane Protein 3 (IFITM3) (N-Term) antibodyVerified IFITM3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- WB: 1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))
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别名
- IFITM3
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背景
- IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
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分子量
- 14632
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UniProt
- Q01628
抗原
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