GAB1 抗体
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北京 101111
Quick Overview for GAB1 抗体 (ABIN6243205)
抗原
See all GAB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This Gab1 antibody is generated from mice immunized with a GST fusion protein encoding full length human GAB1.
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亚型
- IgG1
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anti-GRB2-Associated Binding Protein 1 (GAB1) antibody
GAB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1AT1979 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (AA 250-285) antibodyGAB1 适用: 人 WB 宿主: 兔 Polyclonal RB47324 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (pTyr659) antibodyGAB1 适用: 人 DB 宿主: 兔 Polyclonal RB10842 unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (AA 250-285) antibodyGAB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Associated Binding Protein 1 (GAB1) (pTyr659) antibodyGAB1 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).
: "Role of Gab1 in UV-induced c-Jun NH2-terminal kinase activation and cell apoptosis." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1531-9, (2004) (PubMed).
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: "Acquired substrate preference for GAB1 protein bestows transforming activity to ERBB2 kinase lung cancer mutants." in: The Journal of biological chemistry, Vol. 288, Issue 23, pp. 16895-904, (2013) (PubMed).
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- GAB1 (GRB2-Associated Binding Protein 1 (GAB1))
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别名
- Gab1
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背景
- The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 76616
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NCBI登录号
- NP_002030, NP_997006
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UniProt
- Q13480
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
抗原
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