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DNMT3B 抗体 (AA 356-390)

DNMT3B 适用: 小鼠 WB 宿主: 兔 Polyclonal RB50993 unconjugated
产品编号 ABIN6243167
发货至: 中国
  • 抗原 See all DNMT3B 抗体
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    抗原表位
    • 18
    • 16
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-390
    适用
    • 81
    • 55
    • 35
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 78
    • 4
    • 2
    • 1
    克隆类型
    • 72
    • 13
    多克隆
    标记
    • 35
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DNMT3B antibody is un-conjugated
    应用范围
    • 73
    • 36
    • 24
    • 22
    • 14
    • 13
    • 11
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Dnmt3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 356-390 amino acids from the Central region of Mouse Dnmt3b.
    克隆位点
    RB50993
    亚型
    Ig Fraction
    Top Product
    Discover our top product DNMT3B Primary Antibody
  • 应用备注
    WB: 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
    别名
    Dnmt3b (DNMT3B 产品)
    别名
    DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
    背景
    Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co- repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Function as transcriptional corepressor by associating with ZHX1 (By similarity).
    分子量
    97228
    UniProt
    O88509
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