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PPIF 抗体 (C-Term)

This anti-PPIF antibody is a 兔 多克隆 antibody detecting PPIF in WB. Suitable for 人.
产品编号 ABIN6243145
发货至: 中国

Quick Overview for PPIF 抗体 (C-Term) (ABIN6243145)

抗原

See all PPIF 抗体
PPIF (Peptidylprolyl Isomerase F (PPIF))

适用

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宿主

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克隆类型

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多克隆

标记

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This PPIF antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB49693
  • 抗原表位

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    AA 183-217, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PPIF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-217 amino acids from the C-terminal region of human PPIF.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    PPIF (Peptidylprolyl Isomerase F (PPIF))

    别名

    PPIF

    背景

    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probablity of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress- induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

    分子量

    22040

    UniProt

    P30405

    途径

    Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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