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MME 抗体 (AA 472-505)

Name: MME 抗体 (AA 472-505)
SKU: ABIN6243087
Availability: OutOfStock

MME 适用: 人 FACS, WB, IHC (p) 宿主: 小鼠 Monoclonal 965CT9-1-1 unconjugated

All lanes : Anti-E Antibody (Center) at 1:4000 dilution Lane 1: Human placenta lysate Lane 2: Ramos whole cell lysate Lane 3: Human kidney lysate Lysates/proteins at 20 μg per lane. (MME 抗体 (AA 472-505))

Immunohistochemical analysis of paraffin-embedded human kidney tissue using (ABIN6243087 and ABIN6577253) performed on the Leica® BOND RXm. (MME 抗体 (AA 472-505))

IHC (p)

Immunohistochemical analysis of paraffin-embedded Human kidney section using Pink1 (ABIN6243087 and ABIN6577253). (MME 抗体 (AA 472-505))

IHC

Overlay histogram showing Jurkat cells stained with (ABIN6243087 and ABIN6577253)(green line). (MME 抗体 (AA 472-505))

FACS

4 images

产品编号 ABIN6243087

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
抗原表位
16

14

10

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 472-505
适用
206

58

50

3

2

2

2

2

2

1

1

1

1
人
宿主
111

101

2
小鼠
Compatible Secondaries
克隆类型
108

105

2
单克隆
标记
107

19

18

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
131

96

78

67

35

28

21

20

13

13

10

8

6

5

5

3

2

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is purified through a protein G column, followed by dialysis against PBS.

免疫原

This MME antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 472-505 amino acids from the Central region of human MME.

克隆位点

965CT9-1-1

亚型

IgG1 kappa

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
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应用备注

WB: 1:4000. IHC: 1:1000. IHC-P-Leica: 1:1000. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

MME (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

背景

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675, PubMed:< a href="http://www.uniprot.org/citations/8168535" target="_blank">8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:< a href="http://www.uniprot.org/citations/17101991" target="_blank">17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:< a href="http://www.uniprot.org/citations/15283675" target="_blank">15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:< a href="http://www.uniprot.org/citations/2531377" target="_blank">2531377, PubMed:< a href="http://www.uniprot.org/citations/2972276" target="_blank">2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:< a href="http://www.uniprot.org/citations/20876573" target="_blank">20876573).

分子量

85514

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration