我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

MAP1LC3A 抗体 (AA 30-56)

Name: MAP1LC3A 抗体 (AA 30-56)
SKU: ABIN6243032
Availability: OutOfStock

This anti-MAP1LC3A antibody is a 兔多克隆 antibody detecting MAP1LC3A in WB, IF 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of LC3 (G8a) (arrow) using purified Pab 1801b. (MAP1LC3A 抗体 (AA 30-56))

Forlin-fixed and paraffin-embedded heart muscle tissue reacted with Autophagy LC3 G8a (M1LC3A) Antibody (P45) 1801b , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (MAP1LC3A 抗体 (AA 30-56))

IHC (p)

Fluorescent image of cells stained with (ABIN6243032 and ABIN6577351) LC3 (G8A) (P45) antibody. (MAP1LC3A 抗体 (AA 30-56))

3 images

(2 references)

产品编号 ABIN6243032

发货至: 中国

Datasheet as PDF

Quick Overview for MAP1LC3A 抗体 (AA 30-56) (ABIN6243032)

抗原

See all MAP1LC3A 抗体

MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MAP1LC3A antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB11840

Discover our top product MAP1LC3A Primary Antibody

抗原表位
20

15

14

11

10

7

7

7

6

5

5

5

5

4

4

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 30-56

预测反应

Zf, B, M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This LC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-56 amino acids from human LC3.

亚型

Ig Fraction
anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 89-120), (cleaved) antibody
MAP1LC3A 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal RB38908 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B10D8 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7481 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-120) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody
MAP1LC3A 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 166AT1234 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-30), (N-Term), (pSer12) antibody
MAP1LC3A 适用: 人 WB, DB, EIA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody
MAP1LC3A 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 1-121) antibody
MAP1LC3A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7E9E12 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) (AA 77-106), (C-Term) antibody
MAP1LC3A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7485 unconjugated

应用备注

IF: 1:100. WB: 1:1000. IHC-P: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Lu, Hsu: "Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii)." in: Age (Dordrecht, Netherlands), Vol. 37, Issue 2, pp. 33, (2015) (PubMed).

Hsu, Chuang, Chan: "Changes in cellular degradation activity in young and old worker honeybees (Apis mellifera)." in: Experimental gerontology, Vol. 50, pp. 128-36, (2014) (PubMed).
抗原

MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

别名

LC3

背景

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3a is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.

NCBI登录号

NP_115903, NP_852610

UniProt

Q9H492, Q9GZQ8

途径

Autophagy