HTR2C 抗体 (AA 274-308)
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北京 101111
Quick Overview for HTR2C 抗体 (AA 274-308) (ABIN6243011)
抗原
See all HTR2C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 274-308
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HTR2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 274-308 amino acids from the Central region of human HTR2C.
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亚型
- Ig Fraction
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anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (N-Term) antibody
HTR2C 适用: 人, 小鼠, 大鼠, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Internal Region) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 387-446) antibodyHTR2C 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) antibodyHTR2C 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 9H8 unconjugated Recombinant Antibody
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) antibodyHTR2C 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2025 unconjugated Recombinant Antibody
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (Cytoplasmic Domain) antibodyHTR2C 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 1-52) antibodyHTR2C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (C-Term) antibodyHTR2C 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 243-256), (Extracellular) antibodyHTR2C 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C) (AA 311-410) antibodyHTR2C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))
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别名
- HTR2C
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背景
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1- 2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.
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分子量
- 51821
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UniProt
- P28335
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途径
- Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
抗原
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