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- 抗原 See all CDK8 抗体
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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抗原表位
- AA 424-458, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Cdk8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 424-458 amino acids from the C-terminal region of Mouse Cdk8.
- 克隆位点
- RB51053
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CDK8 Primary Antibody
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anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 375-464) antibody
CDK8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H5 unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 365-464) antibodyCDK8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 21-392) antibodyCDK8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (N-Term) antibodyCDK8 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (C-Term) antibodyCDK8 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 马, 兔, Cow, 小鸡, 非洲爪蟾, Pig, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) antibodyCDK8 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Cyclin-Dependent Kinase 8 (CDK8) (AA 1-30), (N-Term) antibodyCDK8 适用: 人 WB 宿主: 兔 Polyclonal RB3200 unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
- 别名
- Cdk8 (CDK8 产品)
- 背景
- Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. Phosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression. Recruited through interaction with MAML1 to hyperphosphorylate the intracellular domain of NOTCH, leading to its degradation (By similarity).
- 分子量
- 53210
- UniProt
- Q8R3L8
- 途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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