UNC5B 抗体 (AA 507-541)
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北京 101111
Quick Overview for UNC5B 抗体 (AA 507-541) (ABIN6242756)
抗原
See all UNC5B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 507-541
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This UNC5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 507-541 amino acids from the Central region of human UNC5B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- UNC5B (Netrin receptor UNC5B (UNC5B))
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别名
- UNC5B
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背景
- Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity.
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分子量
- 103638
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UniProt
- Q8IZJ1
抗原
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