VAV3 抗体 (C-Term)
Quick Overview for VAV3 抗体 (C-Term) (ABIN6242692)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 768-802, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This VAV3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 768-802 amino acids from the C-terminal region of human VAV3.
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亚型
- Ig Fraction
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anti-Vav 3 Oncogene (VAV3) (AA 183-380) antibody
VAV3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (Internal Region) antibodyVerified VAV3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 701-800) antibodyVAV3 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 560-680) antibodyVAV3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 398-583) antibodyVAV3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 562-674) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) antibodyVAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- VAV3
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背景
- Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1- induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required for the phagocytotic cup formation preceding macrophage phagocytosis of apoptotic neutrophils. Responsible for integrin beta-2 (ITGB2)-mediated macrophage adhesion and, to a lesser extent, contributes to beta-3 (ITGB3)- mediated adhesion. Does not affect integrin beta-1 (ITGB1)- mediated adhesion (By similarity).
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分子量
- 97776
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UniProt
- Q9UKW4
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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