TYRO3 抗体 (C-Term)
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Quick Overview for TYRO3 抗体 (C-Term) (ABIN6242617)
抗原
See all TYRO3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 854-878, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TYRO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 854-878 amino acids from the C-terminal region of human TYRO3.
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亚型
- Ig Fraction
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anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 50-150) antibodyTYRO3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 728-873) antibodyTYRO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 346-361), (Extracellular) antibodyTYRO3 适用: 小鼠 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2520 unconjugated Recombinant Antibody
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 1-890) antibodyTYRO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibodyTYRO3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 10E11 unconjugated
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应用备注
- WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))
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别名
- TYRO3
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背景
- Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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分子量
- 96905
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UniProt
- Q06418
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途径
- RTK signaling
抗原
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