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TYRO3 抗体 (C-Term)

This anti-TYRO3 antibody is a 兔多克隆 antibody detecting TYRO3 in WB. Suitable for 大鼠.

Western blot analysis of lysate from rat brain tissue lysate, using TYRO3 Antibody (C-term) (ABIN6242617 and ABIN6577754). (TYRO3 抗体 (C-Term))

1 image

产品编号 ABIN6242617

发货至: 中国

Quick Overview for TYRO3 抗体 (C-Term) (ABIN6242617)

抗原

See all TYRO3 抗体

TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This TYRO3 antibody is un-conjugated

应用范围

36
25
17
10
9
8
8
3
2
1
1
1
1
1
1

Western Blotting (WB)

克隆位点

RB50580

Discover our top product TYRO3 Primary Antibody

抗原表位
5

5

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 854-878, C-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This TYRO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 854-878 amino acids from the C-terminal region of human TYRO3.

亚型

Ig Fraction
anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 4C8 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 5B4 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IHC, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C4 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 50-150) antibody
TYRO3 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F6 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 728-873) antibody
TYRO3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 1-890) antibody
TYRO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 138-321) antibody
TYRO3 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 6D6F10 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) antibody
TYRO3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 10E11 unconjugated

anti-TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 842-873), (C-Term) antibody
TYRO3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1489 unconjugated

应用备注

WB: 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
抗原

TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

别名

TYRO3

背景

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

分子量

96905

UniProt

Q06418

途径

RTK signaling

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