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PDCD6 抗体 (AA 103-137)

This anti-PDCD6 antibody is a 兔 多克隆 antibody detecting PDCD6 in WB. Suitable for 小鼠.
产品编号 ABIN6242573
发货至: 中国

Quick Overview for PDCD6 抗体 (AA 103-137) (ABIN6242573)

抗原

See all PDCD6 抗体
PDCD6 (Programmed Cell Death 6 (PDCD6))

适用

  • 44
  • 10
  • 9
小鼠

宿主

  • 41
  • 3

克隆类型

  • 41
  • 3
多克隆

标记

  • 16
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This PDCD6 antibody is un-conjugated

应用范围

  • 26
  • 22
  • 13
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB49787
  • 抗原表位

    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 103-137

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    PDCD6 (Programmed Cell Death 6 (PDCD6))

    别名

    PDCD6

    背景

    Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.

    分子量

    21868

    UniProt

    O75340

    途径

    Positive Regulation of Endopeptidase Activity
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