PDCD6 抗体 (AA 103-137)
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北京 101111
Quick Overview for PDCD6 抗体 (AA 103-137) (ABIN6242573)
抗原
See all PDCD6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 103-137
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6.
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亚型
- Ig Fraction
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anti-Programmed Cell Death 6 (PDCD6) (AA 32-191) antibody
PDCD6 适用: 人 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 (PDCD6) (AA 92-191) antibodyPDCD6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-Programmed Cell Death 6 (PDCD6) (AA 1-191) antibodyPDCD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 (PDCD6) (AA 1-191) antibodyPDCD6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 (PDCD6) antibodyPDCD6 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 (PDCD6) antibodyPDCD6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 (PDCD6) (AA 19-47), (N-Term) antibodyPDCD6 适用: 人 WB 宿主: 兔 Polyclonal RB41816 unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PDCD6 (Programmed Cell Death 6 (PDCD6))
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别名
- PDCD6
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背景
- Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.
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分子量
- 21868
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UniProt
- O75340
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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