RAD9A 抗体 (C-Term)
Quick Overview for RAD9A 抗体 (C-Term) (ABIN6242553)
抗原
See all RAD9A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 279-313, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Rad9a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 279-313 amino acids from the C-terminal region of Mouse Rad9a.
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亚型
- Ig Fraction
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anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 162-391) antibody
RAD9A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (Center) antibodyRAD9A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A 适用: 人, 猴, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5D9 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (pSer328) antibodyRAD9A 适用: 人 WB, IHC (p), DB 宿主: 兔 Polyclonal RB7115 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 267-341) antibodyRAD9A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) antibodyRAD9A 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 29-62), (N-Term) antibodyRAD9A 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52362 unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (C-Term) antibodyVerified RAD9A 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (C-Term) antibodyRAD9A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAD9 Homolog A (S. Pombe) (RAD9A) (AA 365-391) antibodyRAD9A 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB29524 unconjugated
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应用备注
- WB: 1:2000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
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别名
- Rad9a
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背景
- Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase. RAD9A possesses 3'->5' double stranded DNA exonuclease activity (By similarity).
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分子量
- 42059
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UniProt
- Q9Z0F6
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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