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KIT Ligand 抗体 (C-Term)

This anti-KIT Ligand antibody is a 兔 多克隆 antibody detecting KIT Ligand in WB. Suitable for 人.
产品编号 ABIN6242418
发货至: 中国

Quick Overview for KIT Ligand 抗体 (C-Term) (ABIN6242418)

抗原

See all KIT Ligand (KITLG) 抗体
KIT Ligand (KITLG)

适用

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宿主

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克隆类型

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多克隆

标记

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This KIT Ligand antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB50736
  • 抗原表位

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    AA 201-234, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This KITLG antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 201-234 amino acids from the C-terminal region of human KITLG.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    KIT Ligand (KITLG)

    别名

    KITLG

    背景

    Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5- trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

    分子量

    30899

    UniProt

    P21583

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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