Importin 9 抗体 (AA 1-388)
Quick Overview for Importin 9 抗体 (AA 1-388) (ABIN6242408)
抗原
See all Importin 9 (IPO9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-388
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This RANBP9 antibody is generated from a mouse immunized with a recombinant protein between 1-388 amino acids from the human RANBP9.
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亚型
- IgG1 kappa
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应用备注
- WB: 1:2000-1:4000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- Importin 9 (IPO9)
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别名
- RANBP9
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背景
- May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).
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分子量
- 77847
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UniProt
- Q96S59
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途径
- Protein targeting to Nucleus
抗原
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