SETD2 抗体 (N-Term)
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北京 101111
Quick Overview for SETD2 抗体 (N-Term) (ABIN6242388)
抗原
See all SETD2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 21-50, N-Term
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预测反应
- M
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This SET2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21~50 amino acids from the N-terminal region of human SET2.
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亚型
- Ig Fraction
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anti-SET Domain Containing 2 (SETD2) (AA 2054-2245) antibody
SETD2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4G11E6 unconjugated
anti-SET Domain Containing 2 (SETD2) (N-Term) antibodySETD2 适用: 人, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (N-Term) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) antibodySETD2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 323-372) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
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: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
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- SETD2 (SET Domain Containing 2 (SETD2))
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别名
- SET2
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背景
- SET2 is a histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This protein probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. SET2 binds DNA at promoters, and may act as a transcription activator. SET2 binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SET2 belongs to a class of huntingtin interacting proteins characterized by WW motifs.
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分子量
- 287597
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NCBI登录号
- NP_054878
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UniProt
- Q9BYW2
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途径
- Tube Formation
抗原
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